Joanne Lager Selected Research

XL765

1/2018	A phase I dose-escalation study of the safety and pharmacokinetics of a tablet formulation of voxtalisib, a phosphoinositide 3-kinase inhibitor, in patients with solid tumors.
10/2016	Phase Ib trial of the PI3K/mTOR inhibitor voxtalisib (SAR245409) in combination with chemoimmunotherapy in patients with relapsed or refractory B-cell malignancies.

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Joanne Lager Research Topics

Disease

8	Neoplasms (Cancer) 09/2021 - 03/2015
1	Disease Progression 07/2017
1	Wernicke Encephalopathy (Wernicke's Encephalopathy) 07/2017
1	Primary Myelofibrosis (Myelosclerosis) 07/2017
1	Non-Hodgkin Lymphoma (Lymphosarcoma) 10/2016
1	Mantle-Cell Lymphoma (Lymphoma, Mantle Cell) 10/2016
1	Lymphoma (Lymphomas) 07/2015
1	B-Cell Chronic Lymphocytic Leukemia (Chronic Lymphocytic Leukemia) 07/2015
1	Diarrhea 03/2015
1	Exanthema (Rash) 03/2015
1	Fatigue 03/2015

Drug/Important Bio-Agent (IBA)

5	XL147IBA 01/2018 - 03/2015
4	TabletsIBA 01/2018 - 03/2015
3	Capsules (Microcapsules)IBA 01/2018 - 01/2017
3	Phosphatidylinositols (Phosphatidylinositol)IBA 01/2018 - 10/2016
2	XL765IBA 01/2018 - 10/2016
1	Granulocyte-Macrophage Colony-Stimulating Factor (GM-CSF)IBA 09/2021
1	Interleukin-15 (Interleukin 15)IBA 09/2021
1	AntibodiesIBA 09/2021
1	CytokinesIBA 09/2021
1	Messenger RNA (mRNA)IBA 09/2021
1	RNA (Ribonucleic Acid)IBA 09/2021
1	Interleukin-12 (IL 12)IBA 09/2021
1	InterferonsIBA 09/2021
1	seribantumabIBA 07/2017
1	ruxolitinibIBA 07/2017
1	fedratinibIBA 07/2017
1	Carboplatin (JM8)FDA LinkGeneric 01/2017
1	Mitogen-Activated Protein KinasesIBA 01/2017
1	Paclitaxel (Taxol)FDA LinkGeneric 01/2017
1	Bendamustine Hydrochloride FDA Link 10/2016
1	Rituximab (Mabthera)FDA Link 10/2016
1	Sirolimus (Rapamycin)FDA Link 10/2016
1	Erlotinib Hydrochloride (CP 358,774)FDA Link 03/2015

Therapy/Procedure

1	Immunotherapy 09/2021